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10.1074/jbc.M203368200 189

GHK-Cu (glycyl-L-histidyl-L-lysine bound to copper) is a naturally occurring copper-binding tripeptide known for its regenerative, antioxidant, and anti-inflammatory functions

In ApoE / mice models, Inhibition of ferroptosis and lipid peroxidation by GPX4 and Fer-1 use further attenuated atherosclerosis [31, 132]

Astrocytes participate in glutamate uptake, they may neutralize its toxic effect, prevent overactivation of microglia, boost immunological responses, and reduce myelin regeneration [27, 40]

Lyophilized GHK-Cu should be stored at -20C and protected from light, as the copper complex can undergo photodegradation